| Top 20 Ghana Music Video Countdown brought to you by Ghana Music. |
| Week #48 Ending December 4th, 2021. | P | W | L | |
| 1. | Abotrɛ (Patience) by Amerado ft. Black Sherif | 1 | 6 | 1 |
| 2. | Mon Bebe by KiDi | 2 | 3 | 3 |
| 3. | Be Afraid (Remix) by Shatta Wale & Medikal | 2 | 3 | 2 |
| 4. | Break My Waist (BMW) by Wendy Shay | 4 | 2 | 6 |
| 5. | Baby by Labena ft. Mr Drew | 4 | 2 | 4 |
| 6. | Assignment by KiddBlack ft. Black Sherif | 6 | 2 | 8 |
| 7. | Sɛkɛ by Mr Drew ft. Medikal | 1 | 3 | 7 |
| 8. | School Dey Be by Foto Copy ft. Shatta Wale | 8 | 4 | 10 |
| 9. | Fever by S3fa ft. Sarkodie & DJ Tira | 9 | 3 | 11 |
| 10. | Greedy Men by Stonebwoy | 5 | 5 | 5 |
| 11. | Thy Grace by Kofi Kinaata | 1 | 7 | 9 |
| 12. | Are You Mad by Edem ft. Kelvyn Boy | 12 | 1 | – |
| 13. | Asuoden by Sista Afia & Kuami Eugene | 13 | 2 | 18 |
| 14. | Sheege by D-Black ft. Gyakie | 5 | 6 | 14 |
| 15. | Abodie by Captain Planet(4×4) ft. Kuami Eugene | 5 | 10 | 13 |
| 16. | Picture by Samini ft. Efya | 7 | 6 | 12 |
| 17. | Je M’appelle by Darkovibes ft. Davido | 1 | 11 | 15 |
| 18. | Sugarcane by Camidoh | 18 | 2 | 19 |
| 19. | For (Cry) by Mr Drew ft. Kwabena Kwabena | 8 | 8 | 17 |
| 20. | Fakye by Ras Kuuku | 18 | 3 | 20 |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top20GHMusicVideos Compiled every week by Ghana Music. |
