| Top 20 Ghana Music Video Countdown brought to you by Ghana Music. |
| Week #46 Ending November 20th, 2021. | P | W | L | |
| 1. | Sɛkɛ by Mr Drew ft. Medikal | 1 | 1 | – |
| 2. | Be Afraid (Remix) by Shatta Wale & Medikal | 2 | 1 | – |
| 3. | Abotrɛ (Patience) by Amerado ft. Black Sherif | 3 | 4 | 4 |
| 4. | Mon Bebe by KiDi | 4 | 1 | 1 |
| 5. | Thy Grace by Kofi Kinaata | 1 | 5 | 1 |
| 6. | Greedy Men by Stonebwoy | 6 | 3 | 10 |
| 7. | Je M’appelle by Darkovibes ft. Davido | 1 | 9 | 2 |
| 8. | Picture by Samini ft. Efya | 7 | 4 | 7 |
| 9. | Abodie by Captain Planet(4×4) ft. Kuami Eugene | 5 | 8 | 8 |
| 10. | Bolga by Bhadext Cona | 3 | 3 | 3 |
| 11. | Sheege by D-Black ft. Gyakie | 5 | 4 | 5 |
| 12. | Last Verse by Strongman | 12 | 4 | 12 |
| 13. | Bunker by Kuami Eugene | 3 | 7 | 6 |
| 14. | Heat by Wendy Shay ft. Shay Gang | 2 | 11 | 9 |
| 15. | Fever by Sefa ft. Sarkodie & DJ Tira | 15 | 1 | – |
| 16. | School Dey Be by Foto Copy ft. Shatta Wale | 16 | 2 | 18 |
| 17. | For (Cry) by Mr Drew ft. Kwabena Kwabena | 8 | 6 | 13 |
| 18. | Fakye by Ras Kuuku | 18 | 1 | – |
| 19. | The Glory by Obaapa Christy | 19 | 2 | 20 |
| 20. | Sika Besu by Amerado ft. Kweku Flick & YPee | 15 | 6 | 15 |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top20GHMusicVideos Compiled every week by Ghana Music. |
