| Top 20 Ghana Music Video Countdown brought to you by Ghana Music. |
| Week #41 Ending October 16th, 2021. | P | W | L | |
| 1. | Je M’appelle by Darkovibes ft. Davido | 1 | 4 | 1 |
| 2. | Awurade Ye by Diana Hamilton | 2 | 5 | 2 |
| 3. | Bunker by Kuami Eugene | 3 | 2 | 3 |
| 4. | Heat by Wendy Shay ft. Shay Gang | 3 | 6 | 4 |
| 5. | Haters by Patapaa ft. Wendy Shay & Twicy | 5 | 3 | 6 |
| 6. | Abodie by Captain Planet(4Ă—4) ft. Kuami Eugene | 6 | 3 | 8 |
| 7. | Attack by Kweku Flick ft. Strongman | 5 | 4 | 5 |
| 8. | Mr Drew ft. Kwabena Kwabena | 8 | 1 | – |
| 9. | OK by Nautyca ft. Michy | 9 | 4 | 14 |
| 10. | Love Locked Down by Okyeame Kwame ft. Adina | 10 | 2 | 16 |
| 11. | Kiss And Tell by D-Black ft. Akwaboah | 11 | 4 | 15 |
| 12. | Ntro Naa by Akwaboah | 9 | 3 | 9 |
| 13. | Nhyira by Strongman ft. Akwaboah | 4 | 9 | 13 |
| 14. | All Correct by DJ Vyrusky ft. Adina & Kuami Eugene | 14 | 1 | – |
| 15. | Second Sermon by Black Sherif | 2 | 13 | 7 |
| 16. | Coachella by Sarkodie ft. Kwesi Arthur | 1 | 20 | 10 |
| 17. | No Time by Oseikrom Sikanii ft. Kweku Flick | 17 | 2 | 20 |
| 18. | Sika Besu by Amerado ft. Kweku Flick & YPee | 18 | 1 | – |
| 19. | Hit by Mona 4Reall ft. Stonebwoy | 19 | 1 | – |
| 20. | Overflow by Efe Grace | 20 | 1 | – |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top20GHMusicVideos Compiled every week by Ghana Music. |
