| Top 20 Ghana Music Video Countdown brought to you by Ghana Music. |
| Week #50 Ending December 18th, 2021. | P | W | L | |
| 1. | Abotrɛ (Patience) by Amerado ft. Black Sherif | 1 | 8 | 1 |
| 2. | Eboso by R2Bees | 2 | 2 | 4 |
| 3. | Be Afraid (Remix) by Shatta Wale & Medikal | 2 | 5 | 2 |
| 4. | Mon Bebe by KiDi | 2 | 5 | 3 |
| 5. | Fever by S3fa ft. Sarkodie & DJ Tira | 5 | 5 | 8 |
| 6. | Break My Waist (BMW) by Wendy Shay | 4 | 4 | 5 |
| 7. | Assignment by KiddBlack ft. Black Sherif | 6 | 4 | 7 |
| 8. | Asuoden by Sista Afia & Kuami Eugene | 8 | 4 | 12 |
| 9. | Bordoss by Quamina MP ft. Sarkodie | 9 | 1 | – |
| 10. | Jonathan by AK Songstress | 10 | 2 | 13 |
| 11. | Sɛkɛ by Mr Drew ft. Medikal | 1 | 5 | 9 |
| 12. | Thy Grace by Kofi Kinaata | 1 | 9 | 11 |
| 13. | Baby by Labena ft. Mr Drew | 4 | 4 | 6 |
| 14. | Sika Krom by Niiny Bizzy | 14 | 1 | – |
| 15. | Sheege by D-Black ft. Gyakie | 5 | 8 | 14 |
| 16. | School Dey Be by Foto Copy ft. Shatta Wale | 8 | 6 | 10 |
| 17. | Success by Casmel | 17 | 1 | – |
| 18. | Don Ding by Kelvyn Boy | 18 | 2 | 20 |
| 19. | 4Eva by Eno Barony ft. Yaw Tog | 19 | 1 | – |
| 20. | Sound of Heaven by Efe Grace | 19 | 2 | 19 |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top20GHMusicVideos Compiled every week by Ghana Music. |
Watch on Top 20 Ghana Music Videos on YouTube
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