| Ghana Music Top 10 Countdown brought to you by Sprog Store. |
| Week #20 May 22nd, 2021. | P | W | L | |
| 1. | Sika Aba Fie by Kweku Darlington ft. Kweku Flick & Yaw Tog | 1 | 9 | 1 |
| 2. | Forever by Gyakie | 1 | 13 | 2 |
| 3. | Dollar On You by Kuami Eugene | 3 | 3 | 6 |
| 4. | Spiritual by KiDi ft. Kuami Eugene & Patoranking | 2 | 14 | 4 |
| 5. | Biibi Besi by Kwame Yogot ft. Kuami Eugene | 2 | 10 | 3 |
| 6. | Baajo by Kwesi Arthur ft. Joeboy | 3 | 11 | 5 |
| 7. | No Fugazy by Sarkodie | 7 | 2 | 9 |
| 8. | Na Today – Okese1 | 6 | 6 | 7 |
| 9. | Mood by Mr Drew | 7 | 4 | 8 |
| 10. | 1st Sermon by Black Sherif | 10 | 1 | – |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top10GH Compiled every week by Ghana Music. |
